What Owners Should Know About Simparica Trio for Dogs

What Owners Should Know About Simparica Trio for Dogs

Author WDF Staff


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Protecting dogs against different types of parasites is something all dog owners need to do. However, that can be challenging, especially if your vet prescribes different medications for various parasites. Some of the worst parasites that can infect your dogs are;

It can be confusing remembering what medication your dog should take and when. If we can choose, we would take a simple medication that provides all-around protection. Luckily, there is Simparica Trio that does exactly that. Here’s what you should know if you are considering this medication for your dog.

What is Simparica Trio?

Simparica Trio can be described as a broad-spectrum parasite preventative that offers protection and treatment to dogs. It is the first drug that combined three active ingredients - sarolaner, moxidectin, and pyrantel. The main goal of this medication, according to the FDA, is;

  • Prevent heartworm disease caused by Dirofilaria immitis
  • Kill adult fleas, treat and prevent flea infestations
  • Treat and control tick infestations with the lone star tick, Gulf Coast tick, American dog tick, black-legged tick, and brown dog tick
  • Treat and control roundworm and adult hookworm infections

That is as good protection as you can ask for. However, there are some crucial questions dog owners want to know the answer to.

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Is it safe for my dog?

The most important question about any chewable tablet is, “Is it safe for my dog?” Protection against parasites is essential, but if risks outweigh the benefits, it might be worth looking into other types of protection. Some dog owners prefer the elegance of chewable preventatives. Still, it makes no sense to give drugs like Simparica Trio to dogs if they are not safe.

Luckily, Simparica Trio for dogs is considered fairly safe. Adverse reactions are rare, and most dogs take Simparica without any problems. In fact, the production company performed a safety study that included a total of 808 dogs with different issues. Some had fleas, some had heartworms, and some had roundworms. Over 11 months (330 days), the study found that all dogs responded well to the treatment.

Simparica Trio side effects

Whenever you introduce medication in your dog’s life, you can expect some side effects. Luckily, dogs treated with Simparica had mild side effects that were gone 24 hours after the initial administration. Nevertheless, some were documented. The most common Simparica Trio for dogs side effects are;

  • Lethargy
  • Vomiting
  • Diarrhea
  • Loss of appetite
  • Polydipsia
  • Polyuria
  • Hyperactivity

Hyperactivity, polydipsia, and polyuria happened in very rare cases. However, they are possible, so it is better to know they might happen.

Is it effective?

The second important question dog owners want to know is, “How effective is Simparica Trio?” According to the same study, the company measured the effectiveness of the drug. Without that data, it would be impossible to get FDA approval. Luckily, the study found the drug is highly effective. Here are some of the most important information about the effectiveness of this drug;

  • Fleas - 100% effectiveness against adult fleas within 24 hours
  • Heartworm - 100% effectiveness against developing heartworm disease
  • Ticks - Kills ticks within 8 hours. 94,7% effective against new infections
  • Roundworms and hookworms - 99,2% effective within 10 days

These are fantastic results, and not many drugs can boost with such numbers. When it comes to prevention, this is the best a dog owner can get.

How is it given to dogs?

Simparica Trio comes in the form of a chewable tablet. Dogs don’t seem to dislike the taste; in fact, they seem to love it. This chewable is liver-flavored, which means most dogs will prefer it. It can be given to dogs with or without food. If your dog vomits when eating the tablet on an empty stomach, give the next dose with some food.

Simparica Trio provides 30-day protection, so it has to be given to dogs once each month. If you are not regular with doses, the effectiveness of the medication can be lowered.

Where can I get it?

The first step of getting the “Simparica Trio” protection or treatment for your dog is visiting your vet. The FDA regulated this drug, and it can only be prescribed by a licensed vet. When you have a valid prescription, you can get it in your local pet pharmacy. If you prefer online orders, you can order it on Chewy’s online pharmacy.

World Dog Finder team

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