When it comes to deworming puppies in the earliest stages of their lives, the Bayer Quad Dewormer might be a great choice. This puppy dewormer can be used when puppies are 3 weeks old, which is a lot sooner than most other dewormers available on the market. The Quad Dewormer will provide protection against four common parasites - Hookworms, Roundworms, Tapeworms, and Whipworms. Since heartworms are passed through mosquito bites, your puppy might be safe from them in the earliest stages of their lives. This is not a prescription dewormer, so you can simply order it online. Make sure you talk to your vet before you decide on any dewormer.

This is the puppy dewormer we have experience with. Our puppy was dewormed with Drontal Plus Chewable Tablet, and we can say we were delighted with its effects on the puppy. Puppies dewormed with this product usually don’t have any side effects, and it was personally recommended by our vet. This is a broad-spectrum dewormer, which means it is effective against different types of worms. It will effectively kill tapeworms, hookworms, roundworms, and whipworms. However, you cannot get it without a valid prescription. If your vet prescribes it, you can pick it up in your local pet pharmacy or order it on Chewy’s online pharmacy.

Droncit is another popular choice by dog breeders and owners around the world. It is mainly prescribed to dogs with tapeworms. However, it contains the active ingredient praziquantel, which is effective against the four most common types of worms. It is a prescription item, so your vet will have to approve it and write you a valid prescription. Like most dewormers, Droncit can cause some side effects. The most common ones are diarrhea, vomiting, and loss of appetite. However, those are acceptable when you know this drug will kill worms within 24 hours of administration. It is a great choice, and it isn’t a surprise many breeders chose this puppy dewormer.

We had to include Advantage Multi Topical Solution on this list because it offers dogs and puppies a wide range of protection. Unlike other dewormers, this one is not an oral medication. This is a topical solution, which means it is effective not only against worms but also against fleas and sarcoptic mange. Another advantage of this dewormer is that it is effective against heartworms. However, it will require a prescription from your vet, so make sure you talk to them first.

We decided to include Sentry Worm X Plus 7 Way DeWormer because it isn’t a prescription item. It offers 30-day protection against 7 different worm species. It is very effective, and after your dog gets used to it, it causes little to no side effects. However, this is a product that can be used on puppies older than 3 months. Keep in mind that just because this product doesn’t require a prescription doesn’t mean you should keep your vet uninformed. Make sure you talk to your vet and ask for their advice. We might be satisfied with this product, but your vet knows your dog’s medical history and can recommend something that might suit your dog better.